Research Technician (Malaria Culturing)

Clearance Level
None
Category
Research
Location
Silver Spring, Maryland

REQ#: RQ92343

Travel Required: Less than 10%
Public Trust: NACI (T1)
Requisition Type: Regular

GDIT is seeking a research technician to provide technical support services necessary to perform entomological research in support of the Entomology Branch at the Walter Reed Army Institute of Research (WRAIR).

The primary research function converge in the development and administration of controlled human malaria infections (CHMI) which is a uniquely intricate method designed to test candidate malaria vaccines by infecting volunteers with malaria via mosquito bites.

The department has or shall use versions of this method to infect non-human primates with dengue virus or Zika virus. This work leads to the development of military-relevant products such as novel vaccines and therapeutics and novel methodologies such as in vitro malaria sporozoite culture.

Responsibilities:

  • Continually maintain parasite life cycle in animal models and mosquitoes or sandflies, to include multiple parasite species and strains maintained concurrently, resulting in hundreds of plates, flasks, and infected animals needing attention each day, depending on demand. Maintaining these cultures might require working weekends based on the number of cultures in process and external requests.
  • Endeavor to improve efficiency, capability or capacity of new and existing culture methods and shall keep abreast of current and emerging literature concerning parasite/viral propagation and culture.
  • Prepare vectors for infectious feeds and infect vectors using appropriate feeding devices, direct animal feeds, or injection methods. Feedings/injections shall occur multiple times a week, sometimes several times a day, and sometimes on weekends, depending on demand.
  • Communicate with supervisors and other personnel to determine demand and adjust production and schedule accordingly.
  • Cultivate and continually maintain parasites, viruses, etc. in tissue culture and maintain laboratory records of parasite/virus growth and differentiation.
  • Monitor parasite/virus development in infected vectors and in vivo animal infections by dissection and microscopic examination or molecular techniques, as appropriate, and maintain laboratory records of parasite/viral development and propagation.
  • Provide a final project record and report which shall include written reports, data summaries, troubleshoot and maintain databases, published research findings in peer-reviewed journals, and presented research findings at scientific meetings and conferences.
  • Be familiar with all cell culture, microbiological, molecular and other applicable techniques and methodology, Biological Safety Level 2 safety procedures, use of laboratory personal protective equipment, be familiar with WRAIR safety standard operating procedures (SOP), and attend WRAIR annual safety courses and other training, as offered.
  • Independently plan, execute and analyze basic research studies on the in vitro and in vivo cultivation of all parasite stages, viral propagation, vector- pathogen interactions, transmission biology and other applicable avenues of scientific investigation.
  • Assist in the preparation of infected vectors and execution of challenges for CHMI clinical trials according to protocol, schedule, and applicable regulatory governance.
  • Assist with the preparation and stewardship of laboratory reagents, methodology, equipment, biological materials and other materials pertaining to experiment execution and laboratory cleanliness and safety.

Required:

  • BS in Biology or scientific related field.
  • 2+ years of experience with all cell culture, microbiological, molecular and other applicable techniques and methodology.
  • Experience with Biological Safety Level (BSL) 2 safety procedures.
  • Experience with the use of laboratory personal protective equipment.
  • Experience assisting with the preparation and stewardship of laboratory reagents, methodology, equipment, biological materials and other materials pertaining to experiment execution and laboratory cleanliness and safety.

Preferred:

  • Experience assisting in the preparation of infected vectors and execution of challenges for CHMI clinical trials according to protocol, schedule, and applicable regulatory governance
  • Experience cultivating and continually maintain parasites, viruses, etc. in tissue culture and maintain laboratory records of parasite/virus growth and differentiation.
  • Experience monitoring parasite/virus development in infected vectors and in vivo animal infections by dissection and microscopic examination or molecular techniques, as appropriate, and maintain laboratory records of parasite/viral development and propagation.

WHAT GDIT CAN OFFER YOU:

  • 401K with company match
  • Customizable health benefits packages
  • Internal mobility team dedicated to helping you own your career
  • Challenging work that makes a real impact on the world around you
  • Full-flex work week

#MILITARYHEALTH

#MILITARYHEALTHGDITJOBS

We are GDIT. The people supporting some of the most complex government, defense, and intelligence projects across the country. We deliver. Bringing the expertise needed to understand and advance critical missions. We transform. Shifting the ways clients invest in, integrate, and innovate technology solutions. We ensure today is safe and tomorrow is smarter. We are there. On the ground, beside our clients, in the lab, and everywhere in between. Offering the technology transformations, strategy, and mission services needed to get the job done.

GDIT is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status, or any other protected class.