GDIT is seeking a Research microbiologist/Bioinformatics Scientist providing genomic analysis support to improve the vaccine virus selection for influenza and SAR-CoV-2.
Background: Genomic surveillance of influenza and SARS-CoV-2 integrated with classic epidemiology facilitates the detection of new epidemic variants and provides complete and accurate information about viruses posing a pandemic threat. The use of genomic epidemiology will improve candidate viruses for pre-pandemic and pandemic vaccine development to assist decision makers in formulating management strategies needed during outbreaks, epidemics, or pandemics.
The ideal candidate will provide genomic analysis support to improve the vaccine virus selection for influenza and SAR-CoV-2.
Responsibilities 1. Conduct genomic epidemiologic studies on the evolution of SARS-CoV-2 and influenza viruses to detect and assess the risk of new emerging variants to current vaccines. 2. Analyze next generation sequence (NGS) data from routine and enhanced global surveillance using spatiotemporal, phylodynamic and epidemiologic approaches to determine trends that can be used in making predictive decisions about prevention, treatment and control prevention, treatment and of influenza/SARS-CoV-2 epidemics or pandemics. 3. Use mathematical and computational approaches to understand, and eventually predict the evolutionary and epidemiological patterns of influenza and SARS-CoV-2 viruses. 4. Collaborate with bioinformaticians on a variety of viral evolution studies related to influenza and SARS-CoV-2 viruses. 5. Ensure the appropriate genomic analysis methods, procedures, techniques, and applicable quality controls are correctly conducted by referring to standard protocols. 6. Plan, prepare materials, coordinate and perform genomic epidemiologic training workshops. 7. Support outbreak response and other activities as needed. 8. Prepare reports, summaries, presentations, papers and other documents to highlight findings, accomplishments, and surveillance data. 9. Participate in special projects and activities and assume responsibilities as assigned. Required Skills and Experience • PhD or Master’s degree in bioinformatics, biostatistics, computational sciences or equivalent field and 3+ years of relevant experience (or equivalent) • Demonstrated experience in NGS data analysis including development and application of quality control, assembly, annotation, sequence alignment, variant detection, and phylogenetic analyses • Working knowledge of disciplines of evolutionary biology, immunology, computational biology, virology, computer science, bioinformatics, and epidemiology sufficient to perform assigned responsibilities • Experience working in Linux environments and broad experience with open source computational tools • Experienced in use of high-performance computing (HPC) clusters • Experience in one or more of the following phylogenetic analysis and visualization tools is highly desirable: BEAST, FastTree, RaxML, TreeTime, NextStrain, Microreact • Proficient coding/scripting in Python, R, Perl
Preferred Skills and Experience • Doctorate degree in bioinformatics, biostatistics, computational sciences or equivalent field and 3+ years of relevant experience (or equivalent) • Proven record of developing analytical approaches, including complex analytical pipelines, for primary and secondary analysis of NGS data • Demonstrated expertise in phylogenetic and phylodynamic analysis of viral species in animal and human populations • Experience with broad data integration including genomic, laboratory, epidemiological and other meta data. • Broad knowledge and expertise in evolutionary biology, immunology, computational biology, virology, computer science, bioinformatics, and epidemiology sufficient to perform assigned responsibilities • Demonstrated experience with SQL and use for data management, integration and reporting • Experience with Tableau, Cloudera (Hadoop)
COVID-19 Vaccination Requirement: To protect the health and safety of its employees and to comply with customer requirements, GDIT may require employees in certain positions to be fully vaccinated against COVID-19. Vaccination requirements will depend on the status of the federal contractor mandate and customer site requirements.
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GDIT is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status, or any other protected class.